Chiral helicity induced by hydrogen bonding and chirality of podand histidyl moieties

被引：49

作者：

Moriuchi, T ^{[1
]}

Nishiyama, M ^{[1
]}

Yoshida, K ^{[1
]}

Ishikawa, T ^{[1
]}

Hirao, T ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 10期

关键词：

D O I：

10.1021/ol0100327

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The single-crystal X-ray structure determination of N,N ' -bis{(S)-(+)-1-methoxycarbonyl-2(4-imidazolyl)ethyl}-2,6-pyridinedicarboxamide (L-BHisPA) and the D-isomer (D-BHisPA) derived from the corresponding chiral histidine revealed a left- and right-handed helical conformation, respectively, through intramolecular hydrogen bonding and chirality of the podand histidyl moieties, Furthermore, each helical molecule is connected by continuous intermolecular hydrogen bonds to afford a left or right handed helical assembly, respectively, in the crystal packing.

引用

页码：1459 / 1461

页数：3

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