Oligoanthranilamides. Non-peptide subunits that show formation of specific secondary structure

被引:259
作者
Hamuro, Y [1 ]
Geib, SJ [1 ]
Hamilton, AD [1 ]
机构
[1] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA
关键词
D O I
10.1021/ja9539857
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.
引用
收藏
页码:7529 / 7541
页数:13
相关论文
共 48 条