How can quality of life researchers make their work more useful to health workers and their patients?

被引:73
作者
Guyatt, Gordon
Schunemann, Holger
机构
[1] McMaster Univ, Hlth Sci Ctr, Dept Clin Epidemiol & Biostat, CLARITY Res Grp, Hamilton, ON L8N 3Z5, Canada
[2] McMaster Univ, Hlth Sci Ctr, Dept Med, Hamilton, ON L8N 3Z5, Canada
[3] Italian Natl Canc Inst Regina Elena, Ist Regina Elena, Div Clin Res Dev & Informat Translat, Dept Epidemiol,INFORMA, I-00144 Rome, Italy
关键词
minimal important difference; number needed to treat; systematic reviews; decision aids;
D O I
10.1007/s11136-007-9223-3
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
To make optimal use of data from randomized trials in clinical decision-making, clinicians require knowledge of the magnitude of treatment effects. Reports of trials including quality of life data often fail to report results that provide interpretable estimates of magnitude of effect. Strategies that investigators could use to remedy this problem include reporting mean differences between groups in relation to the minimal important difference and reporting the proportion of patients who benefit from treatment and the associated number needed to treat. Techniques are available that allow investigators to use the same strategies in reporting pooled estimates from meta-analyses, even when studies use different instruments to measure the same construct. These reporting approaches, as well as ensuring access to data from individual items, will also help those developing decision aids to use quality of life data.
引用
收藏
页码:1097 / 1105
页数:9
相关论文
共 49 条
[11]   Four methods of estimating the minimal important difference score were compared to establish a clinically significant change in Headache Impact Test [J].
Coeytaux, RR ;
Kaufman, JS ;
Chao, R ;
Mann, JD ;
DeVellis, RF .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2006, 59 (04) :374-380
[12]  
Cohen J., 1988, POWERSTATISTICALSCIE, DOI 10.4324/9780203771587
[13]  
DEROSE K, IN PRESS JOINT COMMI
[14]  
DEYO RA, 1984, HEALTH SERV RES, V19, P275
[15]   Post-randomisation exclusions:: the intention to treat principle and excluding patients from analysis [J].
Fergusson, D ;
Aaron, SD ;
Guyatt, G ;
Hébert, P .
BMJ-BRITISH MEDICAL JOURNAL, 2002, 325 (7365) :652-654
[16]  
FLETCHER A, 1988, LANCET, V2, P4
[17]   ABSOLUTELY RELATIVE - HOW RESEARCH RESULTS ARE SUMMARIZED CAN AFFECT TREATMENT DECISIONS [J].
FORROW, L ;
TAYLOR, WC ;
ARNOLD, RM .
AMERICAN JOURNAL OF MEDICINE, 1992, 92 (02) :121-124
[18]   From effect size into number needed to treat [J].
Furukawa, TA .
LANCET, 1999, 353 (9165) :1680-1680
[19]   Exercise self-efficacy in older women with diastolic heart failure - Results of a walking program and education intervention [J].
Gary, Rebecca .
JOURNAL OF GERONTOLOGICAL NURSING, 2006, 32 (07) :31-39
[20]   Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease [J].
Goldstein, RS ;
Todd, TRJ ;
Guyatt, G ;
Keshavjee, S ;
Dolmage, TE ;
van Rooy, S ;
Krip, B ;
Maltais, F ;
LeBlanc, P ;
Pakhale, S ;
Waddell, TK .
THORAX, 2003, 58 (05) :405-410