The origin of new genes:: Glimpses from the young and old

被引：708

作者：

Long, M

Betrán, E

Thornton, K

Wang, W

机构：

[1] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

[2] Univ Chicago, Comm Genet, Chicago, IL 60637 USA

[3] Univ Texas, Dept Biol, Arlington, TX 76019 USA

[4] Chinese Acad Sci, Kunming Inst Zool, Key Lab Cellular & Mol Evolut, CAS Max Planck Jr Scientist Grp, Kunming 650223, Peoples R China

来源：

NATURE REVIEWS GENETICS | 2003年 / 4卷 / 11期

关键词：

D O I：

10.1038/nrg1204

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. However, there has been little opportunity to explore how genes with new functions originate and evolve. The study of ancient genes has highlighted the antiquity and general importance of some mechanisms of gene origination, and recent observations of young genes at early stages in their evolution have unveiled unexpected molecular and evolutionary processes.

引用

页码：865 / 875

页数：11

共 121 条

[1]

[Anonymous], GENOME BIOL

[2] X-chromosome inactivation: Counting, choice and initiation [J].