Research and development needs and opportunities in freeze drying

被引：120

作者：

Liapis, AI

Pikal, MJ

Bruttini, R

机构：

[1] UNIV MISSOURI, BIOCHEM PROC INST, ROLLA, MO 65401 USA

[2] ELI LILLY & CO, LILLY CORP CTR, LILLY RES LABS, INDIANAPOLIS, IN 46285 USA

[3] CRIOFARMA, FREEZE DRYING EQUIPMENT, I-10156 TURIN, ITALY

来源：

DRYING TECHNOLOGY | 1996年 / 14卷 / 06期

关键词：

research and development needs in freeze drying; freeze drying of pharmaceuticals;

D O I：

10.1080/07373939608917146

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Experimental and theoretical research acid development studies are proposed and presented in important areas of the freeze drying process. The practical importance of the synergistic integration of advanced theoretical models and experiments is indicated, and the potential contributions of the proposed studies in the appropriate design, scale-up, control, and prediction of the dynamic behavior of freeze dryers and of the freeze drying process, are presented and discussed.

引用

页码：1265 / 1300

页数：36

共 44 条

[1] FACTORS AFFECTING SHORT-TERM AND LONG-TERM STABILITIES OF PROTEINS [J].