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The cardiovascular toll of stress

被引：516
作者：
Brotman, Daniel J. [1 ]
Golden, Sherita H. [1 ]
Wittstein, Ilan S. [1 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Med, Hospitalist Program, Baltimore, MD 21287 USA
来源：
LANCET | 2007年 / 370卷 / 9592期
关键词：
D O I：
10.1016/S0140-6736(07)61305-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Psychological stress elicits measurable changes in sympathetic-parasympathetic balance and the tone of the hypothalamic-pituitary-adrenal axis, which might negatively affect the cardiovascular system both acutely-by precipitating myocardial infarction, left-ventricular dysfunction, or dysrhythmia; and chronically-by accelerating the atherosclerotic process. We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications.
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页码：1089 / 1100
页数：12
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