Chiral base-mediated benzylic functionalisation of (alkyl benzyl ether)tricarbonylchromium(0) complexes

被引：43

作者：

Cowton, ELM

Gibson, SE

Schneider, MJ

Smith, MH

机构：

[1] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AY,ENGLAND

[2] ASSOC OCTEL CO LTD,WIRRAL L65 4HF,MERSEYSIDE,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 07期

关键词：

D O I：

10.1039/cc9960000839

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric functionalisation of the benzylic methylene group in tricarbonylchromium(0) complexes of alkyl benzyl ethers [(PhCH(2)OR)(CO)(3)Cr-0] is achieved in high yield (86-96%) and high enantiomeric excess (ee) (97 to greater than or equal to 99%) using chiral base methodology.

引用

页码：839 / 840

页数：2

共 22 条

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