The social life of ribosomal proteins

被引：86

作者：

Brodersen, DE ^{[1
]}

Nissen, P ^{[1
]}

机构：

[1] Aarhus Univ, Dept Mol Biol, Ctr Struct Biol, DK-8000 Aarhus, Denmark

来源：

FEBS JOURNAL | 2005年 / 272卷 / 09期

关键词：

crystallography; protein synthesis; ribosomal proteins structure; ribosome; rRNA; translation;

D O I：

10.1111/j.1742-4658.2005.04651.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ribosomal proteins hold a unique position in biology because their function is so closely tied to the large rRNAs of the ribosomes in all kingdoms of life. Following the determination of the complete crystal structures of both the large and small ribosomal subunits from bacteria, the functional role of the proteins has often been overlooked when focusing on rRNAs as the catalysts of translation. In this review we highlight some of the many known and important functions of ribosomal proteins, both during translation on the ribosome and in a wider context.

引用

页码：2098 / 2108

页数：11

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