Novel Brucella strain (BO1) associated with a prosthetic breast implant infection

被引：81

作者：

De, Barun K. ^{[1
]}

Stauffer, Larry ^{[2
]}

Koylass, Mark S. ^{[3
]}

Sharp, Susan E. ^{[4
]}

Gee, Jay E. ^{[1
]}

Helsel, Leta O. ^{[1
]}

Steigerwalt, Arnold G. ^{[1
]}

Vega, Robert ^{[2
]}

Clark, Thomas A. ^{[1
]}

Daneshvar, Maryam I. ^{[1
]}

Wilkins, Patricia P. ^{[1
]}

Whatmore, Adrian M. ^{[3
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[2] Oregon State Publ Hlth Lab, Portland, OR 97201 USA

[3] Vet Labs Agcy, Surrey, England

[4] Kaiser Permanente, Portland, OR 97230 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 01期

关键词：

D O I：

10.1128/JCM.01494-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report the microbiological, biochemical, and molecular characterization of an unusual Brucella strain (BO1) isolated from a breast implant wound in a 71-year-old woman with clinical symptoms consistent with brucellosis. Initial phenotypic analysis, including biochemical and antimicrobial susceptibility testing, cellular fatty acid analysis, and molecular analysis based on DNA-DNA reassociation and the presence of multiple copies of IS711 element suggested that the isolate was a Brucella-like organism, but species determination using microbiological algorithms was unsuccessful. Furthermore, molecular data based on 16S rRNA gene sequencing and multilocus sequence analysis demonstrated that BO1 was an unusual Brucella strain and not closely related to any currently described Brucella species. However, comparison with equivalent sequences in Ochrobactrum spp. confirms that the isolate is much more closely related to Brucella than to Ochrobactrum spp., and thus the isolate likely represents an atypical and novel strain within the genus Brucella.

引用

页码：43 / 49

页数：7

共 47 条

[1] Breast abscess caused by Brucella melitensis [J].