Regulation of gene expression by GC-rich DNA cis-elements

被引:47
作者
Hapgood, JP [1 ]
Riedemann, J [1 ]
Scherer, SD [1 ]
机构
[1] Univ Stellenbosch, Dept Biochem, ZA-7602 Stellenbosch, South Africa
关键词
GC-rich cis-regulatory element; GC box-binding factor; G-strings; gene expression;
D O I
10.1006/cbir.2000.0674
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
GC-rich DNA cis elements are important transcriptional regulatory elements present in the promoter, enhancer and locus control regions of many eukaryotic genes from several species. This review attempts to examine the structure, function and biological significance of GC-rich cis-regulatory elements and their cognate binding proteins, with a view to understanding their role in regulation of gene expression. (C) 2001 Academic Press.
引用
收藏
页码:17 / 31
页数:15
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