Enantioselective asymmetric Pictet-Spengler reaction catalyzed by diisopinocampheylchloroborane

被引：41

作者：

Kawate, T ^{[1
]}

Yamada, H ^{[1
]}

Soe, T ^{[1
]}

Nakagawa, M ^{[1
]}

机构：

[1] CHIBA UNIV,FAC PHARMACEUT SCI,INAGE KU,CHIBA 263,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 05期

关键词：

D O I：

10.1016/0957-4166(96)00134-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The first example of a reagent-controlled enantioselective Pictet-Spengler reaction is demonstrated. Employing diisopinocampheylchloroborane as a chiral Lewis acid catalyst, the Pictet-Spengler reaction of Nb-hydroxytryptamine gave the corresponding 2-hydroxy-tetrahydro-beta-carbolines up to 90 %ee. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1249 / 1252

页数：4

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