Poly(pyrrole-biotin): a new polymer for biomolecule grafting on electrode surfaces

被引:61
作者
Cosnier, S [1 ]
Lepellec, A [1 ]
机构
[1] Univ Grenoble 1, CNRS, UMR 5630, Lab Electrochim Organ & Photochim Redox, F-38041 Grenoble 9, France
关键词
avidin; biotin; biosensor; glucose oxidase; polypyrrole;
D O I
10.1016/S0013-4686(98)00294-1
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
The electropolymerization of a pyrrole-modified biotin by copolymerization with a pyrrole ammonium derivative is described. The resulting copolymer was used for the successive attachment of avidin and biotin-labeled glucose oxidase. This provides an efficient biosensor for the amperometric detection of glucose at 0.6 V SCE (sensitivity: 7 mA M-1 cm(-2)). (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1833 / 1836
页数:4
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