Estimation of excess risk from case-control data using Aalen's linear regression model

被引:7
作者
Borgan, O [1 ]
Langholz, B [1 ]
机构
[1] UNIV SO CALIF,SCH MED,DEPT PREVENT MED,LOS ANGELES,CA 90033
关键词
excess risk; linear hazards model; nested case-control studies; nonparametric methods; survival analysis;
D O I
10.2307/2533968
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We introduce methods for statistical inference in Aalen's non-parametric linear regression model of disease incidence (Aalen, 1989, Statistics in Medicine 8, 907-925) from nested case-control data. These methods provide the basis for estimation of excess risk as a linear function of dose and absolute risk for a given exposure history. The methods are illustrated by estimating excess and absolute risks associated with radon exposure and smoking from nested case-control samples from the Colorado Plateau uranium miners cohort.
引用
收藏
页码:690 / 697
页数:8
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