The human CYP3A subfamily: Practical considerations

被引：183

作者：

Wrighton, SA

Schuetz, EG

Thummel, KE

Shen, DD

Korzekwa, KR

Watkins, PB

机构：

[1] Lilly Corp Ctr, Lilly Res Labs, Dept Drug Disposit, Indianapolis, IN 46285 USA

[2] St Jude Childrens Res Hosp, Dept Pharmaceut Sci, Memphis, TN 38105 USA

[3] Univ Washington, Dept Pharmaceut, Seattle, WA 98195 USA

[4] Univ Washington, Dept Pharm, Seattle, WA 98195 USA

[5] Camitro Corp, Menlo Pk, CA 94025 USA

[6] Univ N Carolina, Chapel Hill, NC 27599 USA

来源：

DRUG METABOLISM REVIEWS | 2000年 / 32卷 / 3-4期

关键词：

D O I：

10.1081/DMR-100102338

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：339 / 361

页数：23

共 104 条

[71] Evidence for the presence of a functional Pregnane X Receptor response element in the CYP3A7 promoter gene [J].

Pascussi, JM ;

Jounaidi, Y ;

Drocourt, L ;

Domergue, J ;

Balabaud, C ;

Maurel, P ;

Vilarem, MJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 260 (02) :377-381

[72] A NOVEL CIS-ACTING ELEMENT IN A LIVER CYTOCHROME-P450 3A GENE CONFERS SYNERGISTIC INDUCTION BY GLUCOCORTICOIDS PLUS ANTIGLUCOCORTICOIDS [J].

QUATTROCHI, LC ;

MILLS, AS ;

BARWICK, JL ;

YOCKEY, CB ;

GUZELIAN, PS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (48) :28917-28923

[73] Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4 [J].

Rebbeck, TR ;

Jaffe, JM ;

Walker, AH ;

Wein, AJ ;

Malkowicz, SB .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (16) :1225-1229

[74] KINETICS OF DRUG-DRUG INTERACTIONS [J].

ROWLAND, M ;

MATIN, SB .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1973, 1 (06) :553-567

[75] Molecular mechanisms of cytochrome P-450 induction by xenobiotics:: An expanded role for nuclear hormone receptors [J].

Savas, Ü ;

Griffin, KJ ;

Johnson, EF .

MOLECULAR PHARMACOLOGY, 1999, 56 (05) :851-857

[76]

SchmiedlinRen P, 1997, DRUG METAB DISPOS, V25, P1228

[77] Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1 alpha,25-dihydroxyvitamin D-3 [J].

SchmiedlinRen, P ;

Thummel, KE ;

Fisher, JM ;

Paine, MF ;

Lown, KS ;

Watkins, PB .

MOLECULAR PHARMACOLOGY, 1997, 51 (05) :741-754

[78] Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element [J].

Schuetz, EG ;

Brimer, C ;

Schuetz, JD .

MOLECULAR PHARMACOLOGY, 1998, 54 (06) :1113-1117

[79]

Schuetz EG, 2000, DRUG METAB DISPOS, V28, P268

[80]

SCHUETZ EG, 1984, J BIOL CHEM, V259, P1999

← 2 3 4 5 6 7 8 9 10 11 →