Highly convenient, one-pot synthesis of nitriles from aldehydes using the NH2OH•HCl/NaI/MeCN system

被引：32

作者：

Ballini, R ^{[1
]}

Fiorini, D ^{[1
]}

Palmieri, A ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

SYNLETT | 2003年 / 12期

关键词：

aldehydes; hydroxylamine hydrochloride; sodium iodide; catalysis; nitriles;

D O I：

10.1055/s-2003-41408

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct transformation of both aliphatic and aromatic aldehydes to the corresponding nitrites, can be easily performed by the reaction of an aldehyde with a slight excess of hydroxylamine hydrochloride. in refluxing acetonitrile and in the presence of 0.5 equivalents of sodium iodide as catalyst.

引用

收藏

页码：1841 / 1843

页数：3

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