Palladium-Catalyzed Elimination/Isomerization of Enol Triflates into 1,3-Dienes

被引：44

作者：

Crouch, Ian T. ^{[1
]}

Dreier, Timothy ^{[1
]}

Frantz, Doug E. ^{[1
]}

机构：

[1] Univ Texas San Antonio, Dept Chem, San Antonio, TX 78249 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 27期

关键词：

dienes; enol triflates; homogeneous catalysis; palladium; synthetic methods; CROSS-COUPLING REACTION; STEREOSELECTIVE-SYNTHESIS; CONJUGATED DIENES; ISOMERIZATION; TOSYLATES; ALKENES; ESTERS; OLEFINATION; METATHESIS; PHOSPHATES;

D O I：

10.1002/anie.201101820

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dying to be Dienes: Substituted 1,3-dienes were synthesized by the title reaction (see scheme; Tf=trifluoromethanesulfonyl). Preliminary studies support a mechanistically distinct pathway that involves an initial β-hydride elimination from a cationic vinyl palladium(II) intermediate, a subsequent regiospecific hydropalladation of the corresponding allene intermediate, and a final β-hydride elimination. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6128 / 6132

页数：5

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