Chemoselective construction of substituted conjugated dienes using an olefin cross-metathesis protocol

被引：103

作者：

Funk, TW ^{[1
]}

Efskind, J ^{[1
]}

Grubbs, RH ^{[1
]}

机构：

[1] CALTECH, Div Chem & Chem Engn, Arnold Mabel Beckman Lab Chem Synth, Pasadena, CA 91125 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 02期

关键词：

D O I：

10.1021/ol047929z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various substituted conjugated dienes have been made by olefin cross-metathesis. Using either electronic or steric "protection,'' one of the olefins of the conjugated diene was deactivated relative to the other for cross-metathesis. The reactions proceed with very high chemoselectivity and, when steric deactivation is used, very high diastereoselectivity.

引用

页码：187 / 190

页数：4

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