Inflammation as a matchmaker: revisiting cell fusion

被引：41

作者：

Singec, Ilyas ^{[1
]}

Snyder, Evan Y. ^{[1
]}

机构：

[1] Inst Med Res, Program Stem Cell & Regenerat Biol, La Jolla, CA 92037 USA

来源：

NATURE CELL BIOLOGY | 2008年 / 10卷 / 05期

关键词：

D O I：

10.1038/ncb0508-503

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

Sporadic fusion of bone-marrow-derived cells with those of developmentally unrelated structures following transplantation has previously been regarded solely as an artefact, leading to the misinterpretation that cells could ' transdifferentiate'. we now learn that heterotypic cell fusion of myelo-lymphoid cells with non-haematopoietic cells is enhanced during chronic inflammation, raising new questions about the biological significance of this controversial phenomenon.

引用

页码：503 / 505

页数：3

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