Liver transplantation of hepatic stem cells: potential use for treating liver diseases

被引：19

作者：

Feldmann, G ^{[1
]}

机构：

[1] Univ Paris 07, CHU Bichat Claude Bernard, Fac Med Xavier Bichat, Lab Biol Cellulaire,INSERM,U327, F-75018 Paris, France

来源：

CELL BIOLOGY AND TOXICOLOGY | 2001年 / 17卷 / 02期

关键词：

hematopoietic stem cells; hepatic stem cells; hepatocytes; liver transplantation; oval cells;

D O I：

10.1023/A:1010954020488

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Hepatic stem cells are an alternative means for repopulating the liver after various injuries instead of liver transplantation. The first step before use is to select stem cells that will be good candidates. This review discusses the different candidates including fetal progenitor bipotential hepatic stem cells; adult hepatocytes, which can be considered as unipotential committed stem cells; and oval cells, a type of nonparenchymal pluripotential hepatic stem cell. The advantages and disadvantages of each type of cell are discussed and several other possible alternatives, such as the use of hematopoietic stem cells are analyzed.

引用

页码：77 / 85

页数：9

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