Ligand-gated channels

被引：36

作者：

Barry, PH ^{[1
]}

Lynch, JW

机构：

[1] Univ New S Wales, Sch Med Sci, Sydney, NSW 2052, Australia

[2] Univ Queensland, Sch Biomed Sci, Brisbane, Qld 4072, Australia

来源：

IEEE TRANSACTIONS ON NANOBIOSCIENCE | 2005年 / 4卷 / 01期

关键词：

acetylcholine receptor channel; channel gating; glycine receptor channel; ion permeation;

D O I：

10.1109/TNB.2004.842497

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Ligand-gated ion channels (LGICs) are fast-responding channels in which the receptor, which binds the activating molecule (the ligand), and the ion channel are part of the same nanomolecular protein complex. This paper will describe the properties and functions of the nicotinic acetylcholine LGIC superfamily, which plays a critical role in the fast chemical transmission of electrical signals between nerve cells and between nerve and muscle cells. The superfamily will mainly be exemplified by the excitatory nicotinic acetylcholine receptor (nAChR) and the inhibitory glycine receptor (GlyR) channels.

引用

页码：70 / 80

页数：11