Cellular and physiological effects of short-chain fatty acids

被引：69

作者：

Miller, SJ ^{[1
]}

机构：

[1] Clarian Hlth Partners Inc, Methodist Res Inst, Expt Pathol Lab, Indianapolis, IN 46202 USA

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2004年 / 4卷 / 08期

关键词：

short chain fatty acids; butyrate; inflammation; cancer; colon and fiber;

D O I：

10.2174/1389557043403288

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.

引用

页码：839 / 845

页数：7

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