Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors

被引:386
作者
Hagness, SC
Taflove, A
Bridges, JE
机构
[1] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA
[2] Northwestern Univ, Mccormick Sch Engn & Appl Sci, Dept Elect & Comp Engn, Evanston, IL 60208 USA
[3] Interstitial Inc, Park Ridge, IL 60068 USA
关键词
biomedical electromagnetic imaging; cancer; FDTD methods; microwave antenna arrays; numerical analysis; scattering; tumors;
D O I
10.1109/10.730440
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, we have conducted a two-dimensional (2-D) finite-difference time-domain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations shelved that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.
引用
收藏
页码:1470 / 1479
页数:10
相关论文
共 43 条
[21]  
Hagness SC, 1997, P ANN INT IEEE EMBS, V19, P2506, DOI 10.1109/IEMBS.1997.756837
[22]  
HEYWANGKOBRUNNER SH, 1992, CURR OPIN RADIOL, V4, P146
[23]   NONIONIZING ELECTROMAGNETIC WAVE EFFECTS IN BIOLOGICAL-MATERIALS AND SYSTEMS [J].
JOHNSON, CC ;
GUY, AW .
PROCEEDINGS OF THE INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS, 1972, 60 (06) :692-&
[24]   THE MEASURED ELECTRICAL-PROPERTIES OF NORMAL AND MALIGNANT HUMAN TISSUES FROM 50 TO 900 MHZ [J].
JOINES, WT ;
ZHANG, Y ;
LI, CX ;
JIRTLE, RL .
MEDICAL PHYSICS, 1994, 21 (04) :547-550
[25]   DIRECT TIME INTEGRATION OF MAXWELL EQUATIONS IN LINEAR DISPERSIVE MEDIA WITH ABSORPTION FOR SCATTERING AND PROPAGATION OF FEMTOSECOND ELECTROMAGNETIC PULSES [J].
JOSEPH, RM ;
HAGNESS, SC ;
TAFLOVE, A .
OPTICS LETTERS, 1991, 16 (18) :1412-1414
[26]  
KEAREY P, 1984, GEOSCIENCE TEXTS, V4, pCH4
[27]   EARLY BREAST-CANCER DETECTION USING TECHNIQUES OTHER THAN MAMMOGRAPHY [J].
KOPANS, DB .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1984, 143 (03) :465-468
[28]  
LICHMAN JW, 1994, SCI AM, V171, P40
[29]  
MONTOYA TP, 1997, P N AM RAD SCI M MON
[30]  
Parsons W.H., 1959, CANC BREAST