Molecular mechanisms of hemoglobin switching

被引：12

作者：

Jane, SM

Cunningham, JM

机构：

[1] ST JUDE CHILDRENS RES HOSP, WALTER & ELIZA HALL INST MED RES, MEMPHIS, TN 38101 USA

[2] ST JUDE CHILDRENS RES HOSP, DIV EXPT HEMATOL, MEMPHIS, TN 38105 USA

[3] UNIV TENNESSEE, DEPT PEDIAT & BIOCHEM, MEMPHIS, TN 38103 USA

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | 1996年 / 28卷 / 11期

关键词：

globin genes; transcription; locus control region; developmental regulation; transcription factors;

D O I：

10.1016/S1357-2725(96)00058-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The developmental regulation of the human beta-globin cluster embodies all aspects of transcriptional control of eukaryotic genes. The cis-acting sequences within the cluster, distal regulatory regions and trans-acting factors all contribute to provide stringent temporal and tissue-specific expression. This review will examine the individual regulatory mechanisms which govern globin gene expression and highlight recent advances which expand our understanding of these dynamic interactions. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1197 / 1209

页数：13

共 116 条

[1] ABEL T, 1994, MOL BASIS BLOOD DIS, P33
[2] PARTICIPATION OF THE HUMAN BETA-GLOBIN LOCUS-CONTROL REGION IN INITIATION OF DNA-REPLICATION
ALADJEM, MI
GROUDINE, M
BRODY, LL
DIEKEN, ES
FOURNIER, REK
WAHL, GM
EPNER, EM
[J]. SCIENCE, 1995, 270 (5237) : 815 - 819
[3] ERYTHROID TRANSCRIPTION FACTOR NF-E2 IS A HEMATOPOIETIC-SPECIFIC BASIC LEUCINE ZIPPER PROTEIN
ANDREWS, NC
ERDJUMENTBROMAGE, H
DAVIDSON, MB
TEMPST, P
ORKIN, SH
[J]. NATURE, 1993, 362 (6422) : 722 - 728
[4] BETA-THALASSEMIA IN AMERICAN BLACKS - NOVEL MUTATIONS IN THE TATA BOX AND AN ACCEPTOR SPLICE SITE
ANTONARAKIS, SE
IRKIN, SH
CHENG, TC
SCOTT, AF
SEXTON, JP
TRUSKO, SP
CHARACHE, S
KAZAZIAN, HH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (04): : 1154 - 1158
[5] DROSOPHILA TISSUE-SPECIFIC TRANSCRIPTION FACTOR NTF-1 CONTAINS A NOVEL ISOLEUCINE-RICH ACTIVATION MOTIF
ATTARDI, LD
TJIAN, R
[J]. GENES & DEVELOPMENT, 1993, 7 (7B) : 1341 - 1353
[6] AN INTRAMOLECULAR TRIPLEX IN THE HUMAN GAMMA-GLOBIN 5'-FLANKING REGION IS ALTERED BY POINT MUTATIONS ASSOCIATED WITH HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN
BACOLLA, A
ULRICH, MJ
LARSON, JE
LEY, TJ
WELLS, RD
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (41) : 24556 - 24563
[7] REGULATED EXPRESSION OF THE BETA-GLOBIN GENE LOCUS IN SYNTHETIC NUCLEI
BARTON, MC
EMERSON, BM
[J]. GENES & DEVELOPMENT, 1994, 8 (20) : 2453 - 2465
[8] BARTON MC, 1993, GENE DEV, V7, P18796
[9] THE GENE SCL IS EXPRESSED DURING EARLY HEMATOPOIESIS AND ENCODES A DIFFERENTIATION-RELATED DNA-BINDING MOTIF
BEGLEY, CG
APLAN, PD
DENNING, SM
HAYNES, BF
WALDMANN, TA
KIRSCH, IR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (24) : 10128 - 10132
[10] 2 3' SEQUENCES DIRECT ADULT ERYTHROID-SPECIFIC EXPRESSION OF HUMAN BETA-GLOBIN GENES IN TRANSGENIC MICE
BEHRINGER, RR
HAMMER, RE
BRINSTER, RL
PALMITER, RD
TOWNES, TM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (20) : 7056 - 7060

← 1 2 3 4 5 6 7 8 9 10 →