Microarrays go live - new prospects for proteomics

被引：10

作者：

Blagoev, B ^{[1
]}

Pandey, A

机构：

[1] Univ So Denmark, Ctr Expt Bioinformat, Odense M, Denmark

[2] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2001年 / 26卷 / 11期

关键词：

D O I：

10.1016/S0968-0004(01)01977-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microarrays have rapidly become popular for high-throughput functional genomic studies. For example, strategies to identify single nucleotide polymorphisms and studies of differential mRNA expression make use of oligonucleotide or DNA microarrays. More recently, protein-based arrays using immobilized fusion proteins or antibodies have been developed, The latest in these innovations is the development of microarrays containing live cells that express a cDNA of interest. These arrays are an excellent complement to DNA and protein 'chips' for high-throughput proteomic studies.

引用

页码：639 / 641

页数：3

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