Metabolomics in the Developing Human Being

被引：34

作者：

Syggelou, Aggeliki ^{[4
]}

Lacovidou, Nicoletta ^{[4
]}

Atzori, Luigi ^{[5
]}

Xanthos, Theodoros ^{[4
]}

Fanos, Vassilios ^{[1
,2
,3
]}

机构：

[1] AOU Cagliari, Inst Puericulture, Neonatal Intens Care Unit, I-09134 Cagliari, Italy

[2] AOU Cagliari, Neonatal Sect, I-09134 Cagliari, Italy

[3] Univ Cagliari, I-09134 Cagliari, Italy

[4] Univ Athens, Sch Med, Athens 11527, Greece

[5] Univ Cagliari, Dept Biomed Sci, I-09124 Cagliari, Italy

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2012年 / 59卷 / 05期

关键词：

Metabolomics; Neonate; Prenatal health; Childhood; ACUTE KIDNEY INJURY; PERSONALIZED MEDICINE; SYSTEMS BIOLOGY; CARDIAC-SURGERY; PRENATAL DISORDERS; CHILDHOOD ASTHMA; URINE; BIOMARKERS; NMR; METABONOMICS;

D O I：

10.1016/j.pcl.2012.07.002

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Metabolomics is based on the detailed analysis of metabolites and represents a unique chemical fingerprint of an organism. This approach allows assessing the dynamic behavior of biologic systems with multiple network interactions among individual components. The field of metabolic profiling has rapidly developed over the last decade, with successful applications in various research areas including toxicology, disease diagnosis and classification, pharmacology, and nutrition. This article provides a comprehensive account of existing data in the literature from animal and clinical studies on the use of metabolomics for improved understanding of medical conditions affecting the neonate and the developing human being.

引用

页码：1039 / +

页数：22

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