Cellulitis revealing a cryptococcosis-related immune reconstitution inflammatory syndrome in a renal allograft recipient

被引:39
作者
Lanternier, F. [1 ]
Chandesris, M.-O. [1 ]
Poiree, S. [1 ]
Bougnoux, M.-E. [1 ]
Mechai, F. [1 ]
Mamzer-Bruneel, M.-F. [1 ]
Viard, J.-P. [1 ]
Galmiche-Rolland, L. [1 ]
Lecuit, M. [1 ]
Lortholary, O. [1 ]
机构
[1] Univ Paris 05, Ctr Infectiol Necker Pasteur, Hop Necker Enfants Malad, Serv Malad Infectieuses & Trop, Paris 15, France
关键词
Cellulitis; cryptococcosis; immune reconstitution inflammatory syndrome; renal allograft transplant;
D O I
10.1111/j.1600-6143.2007.01994.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Immune reconstitution inflammatory syndrome (IRIS) has rarely been described in the course of disseminated cryptococcosis in solid organ transplant recipients. We report here the case of a renal transplant recipient who developed severe cellulitis in the context of Cryptococcus neoformans-associated IRIS while undergoing reduction of his immunosuppressive therapy. IRIS appeared concomitantly with a dramatic increase of blood CD4+ T cells (94-460/mm(3)) and required the administration of a short-term steroid therapy to resolve.
引用
收藏
页码:2826 / 2828
页数:3
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