Cellulitis revealing a cryptococcosis-related immune reconstitution inflammatory syndrome in a renal allograft recipient

被引：39

作者：

Lanternier, F. ^{[1
]}

Chandesris, M.-O. ^{[1
]}

Poiree, S. ^{[1
]}

Bougnoux, M.-E. ^{[1
]}

Mechai, F. ^{[1
]}

Mamzer-Bruneel, M.-F. ^{[1
]}

Viard, J.-P. ^{[1
]}

Galmiche-Rolland, L. ^{[1
]}

Lecuit, M. ^{[1
]}

Lortholary, O. ^{[1
]}

机构：

[1] Univ Paris 05, Ctr Infectiol Necker Pasteur, Hop Necker Enfants Malad, Serv Malad Infectieuses & Trop, Paris 15, France

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2007年 / 7卷 / 12期

关键词：

Cellulitis; cryptococcosis; immune reconstitution inflammatory syndrome; renal allograft transplant;

D O I：

10.1111/j.1600-6143.2007.01994.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Immune reconstitution inflammatory syndrome (IRIS) has rarely been described in the course of disseminated cryptococcosis in solid organ transplant recipients. We report here the case of a renal transplant recipient who developed severe cellulitis in the context of Cryptococcus neoformans-associated IRIS while undergoing reduction of his immunosuppressive therapy. IRIS appeared concomitantly with a dramatic increase of blood CD4+ T cells (94-460/mm(3)) and required the administration of a short-term steroid therapy to resolve.

引用

页码：2826 / 2828

页数：3

共 11 条

[11] Cryptococcus neoformans in organ transplant recipients:: Impact of calcineurin-inhibitor agents on mortality [J].

Singh, Nina ;

Alexander, Barbara D. ;

Lortholary, Olivier ;

Dromer, Francoise ;

Gupta, Krishan L. ;

John, George T. ;

del Busto, Ramon ;

Klintmalm, Goran B. ;

Somani, Jyoti ;

Lyon, G. Marshall ;

Pursell, Kenneth ;

Stosor, Valentina ;

Munoz, Patricia ;

Limaye, Ajit P. ;

Kalil, Andre C. ;

Pruett, Timothy L. ;

Garcia-Diaz, Julia ;

Humar, Atul ;

Houston, Sally ;

House, Andrew A. ;

Wray, Dannah ;

Orloff, Susan ;

Dowdy, Lorraine A. ;

Fisher, Robert A. ;

Heitman, Joseph ;

Wagener, Marilyn M. ;

Husain, Shahid .

JOURNAL OF INFECTIOUS DISEASES, 2007, 195 (05) :756-764

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