Temperature-dependent isomerisation versus net fragmentation of secondary allylic alcohols with Grubbs' catalyst

被引：63

作者：

Gurjar, MK ^{[1
]}

Yakambram, P ^{[1
]}

机构：

[1] Natl Chem Lab, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(01)00449-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Secondary allylic alcohols with 10 mol% of Grubbs catalyst in refluxing toluene/1,2-dichloroethane undergo isomerisation to ethyl ketones whereas with 100 mol% of Grubbs catalyst at room temperature, a net fragmentation reaction with the loss of a carbon atom occurs, to provide a methyl ketone. Probable mechanisms are described. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：3633 / 3636

页数：4

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