Synthesis of 2-hetaryl substituted indoles via palladium-catalysed reductive N-heterocyclisation

被引：17

作者：

Tollari, S

Cenini, S

Rossi, A

Palmisano, G

机构：

[1] Dipartimento Chim Inorgan Met Organ & Analit, I-20133 Milan, Italy

[2] Ctr CNR, I-20133 Milan, Italy

[3] Dipartimento Sci & Tecnol Farm, I-10125 Turin, Italy

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1998年 / 135卷 / 03期

关键词：

synthesis; 2-hetaryl substituted indoles; reductive N-heterocyclisation; palladium catalyst;

D O I：

10.1016/S1381-1169(97)00312-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An improved synthesis of a family of polidendate Ligands embodying indole subunit(s) was performed, via a nitrene insertion as a key step, starting from easily accessible o-nitrostyryl precursors. This transformation was efficiently achieved through the agency of CO in the presence of Pd(2,4,6-trimethylbenzoate)(2) as catalyst and 3,4,7,8-tetramethyl-1,10-phenanthroline as co-ligand. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：241 / 248

页数：8

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