Aspects of the innate and adaptive immune responses to acute infections with BVDV

被引:45
作者
Brackenbury, LS [1 ]
Carr, BV [1 ]
Charleston, B [1 ]
机构
[1] Inst Anim Hlth, Newbury RG20 7NN, Berks, England
关键词
bovine viral diarrhoea virus; interferon; immunosuppression; innate; adaptive; immunity;
D O I
10.1016/j.vetmic.2003.09.004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The immune response can be divided into innate and adaptive components that synergise to effect the clearance of pathogens. Recently, it has been realised that these arms of the immune system do not act independently, the magnitude and quality of the adaptive response is dependent on signals derived from the innate response. Here, we review the innate immune responses to bovine viral diarrhoea virus infections of cattle and relate these changes to immunosuppression and the subsequent development of the adaptive immune response. (C) 2003 Published by Elsevier B.V.
引用
收藏
页码:337 / 344
页数:8
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