Drug development for airway diseases: looking forward

被引：17

作者：

Holgate, Stephen ^{[1
]}

Agusti, Alvar ^{[2
]}

Strieter, Robert M. ^{[3
]}

Anderson, Gary P. ^{[4
]}

Fogel, Robert ^{[5
]}

Bel, Elisabeth ^{[6
]}

Martin, Thomas R. ^{[5
]}

Reiss, Theodore F. ^{[5
]}

机构：

[1] Univ Southampton, Southampton Gen Hosp, Fac Med, Clin & Expt Sci, Southampton SO16 6YD, Hants, England

[2] Univ Barcelona, Ctr Invest Biomed Red Enfermedades Resp CIBERES, Inst Invest Biomed August Pi i Sunyer IDIBAPS, Thorax Inst,Hosp Clin, E-08036 Barcelona, Spain

[3] Novartis Inst BioMed Res, Cambridge, MA 02139 USA

[4] Univ Melbourne, Dept Pharmacol & Therapeut, Lung Hlth Res Ctr, Melbourne, Vic 3010, Australia

[5] Novartis Pharmaceut, E Hanover, NJ 07936 USA

[6] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

来源：

NATURE REVIEWS DRUG DISCOVERY | 2015年 / 14卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1038/nrd4645

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 090105 [作物生产系统与生态工程];

摘要：

Advancing drug development for airway diseases beyond the established mechanisms and symptomatic therapies requires redefining the classifications of airway diseases, considering systemic manifestations, developing new tools and encouraging collaborations.

引用

页码：367 / 368

页数：2

共 5 条

[1]

Personalized Respiratory Medicine: Exploring the Horizon, Addressing the Issues Summary of a BRN-AJRCCM Workshop Held in Barcelona on June 12, 2014 [J].

Agusti, Alvar ;

Anto, Josep Maria ;

Auffray, Charles ;

Barbe, Ferran ;

Barreiro, Esther ;

Dorca, Jordi ;

Escarrabill, Joan ;

Faner, Rosa ;

Furlong, Laura I. ;

Garcia-Aymerich, Judith ;

Gea, Joaquim ;

Lindmark, Bertil ;

Monso, Eduard ;

Plaza, Vicente ;

Puhan, Milo A. ;

Roca, Josep ;

Ruiz-Manzano, Juan ;

Sampietro-Colom, Laura ;

Sanz, Ferran ;

Serrano, Luis ;

Sharpe, James ;

Sibila, Oriol ;

Silverman, Edwin K. ;

Sterk, Peter J. ;

Sznajder, Jacob I. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191 (04) :391-401

[2]

Network Analysis in the Investigation of Chronic Respiratory Diseases [J].

Diez, Diego ;

Agusti, Alvar ;

Wheelock, Craig E. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190 (09) :981-988

[3]

Beyond FEV1 in COPD: a review of patient-reported outcomes and their measurement [J].

Jones, Paul ;

Miravitlles, Marc ;

van der Molen, Thys ;

Kulich, Karoly .

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2012, 7 :697-709

[4]

Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms? [J].

Vanfleteren, Lowie E. G. W. ;

Kocks, Janwillem W. H. ;

Stone, Ian S. ;

Breyer-Kohansal, Robab ;

Greulich, Timm ;

Lacedonia, Donato ;

Buhl, Roland ;

Fabbri, Leonardo M. ;

Pavord, Ian D. ;

Barnes, Neil ;

Wouters, Emiel F. M. ;

Agusti, Alvar .

THORAX, 2014, 69 (01) :72-U89

[5]

Wouters Emiel F M, 2009, Proc Am Thorac Soc, V6, P638, DOI 10.1513/pats.200907-073DP

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