Oxygenated terpenoids from a Formosan soft coral Sinularia gibberosa

被引：39

作者：

Ahmed, AF

Kuo, YH

Dai, CF

Sheu, JH ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Resources, Kaohsiung 804, Taiwan

[2] Mansoura Univ, Fac Pharm, Dept Pharmacognosy, Mansoura 35516, Egypt

[3] Natl Res Inst Chinese Med, Taipei 112, Taiwan

[4] Natl Taiwan Univ, Inst Oceanog, Taipei 106, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 08期

关键词：

D O I：

10.1021/np050114u

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new oxygenated sesquiterpenoids, gibberodione (1), peroxygibberol (2), and sinugibberodiol (3), along with sarcophytol L (4) were isolated from a Formosan soft coral, Sinularia gibberosa. The structures of the new metabolites were determined on the basis of extensive spectroscopic analyses and by comparison of NMR data with those of related metabolites. Metabolites 2 and 4 were found to exhibit moderate cytotoxicity toward a human liver carcinoma cell line.

引用

页码：1208 / 1212

页数：5

共 19 条

[1] New β-caryophyllene-derived terpenoids from the soft coral Sinularia nanolobata
Ahmed, AF
Su, JH
Shiue, RT
Pan, XJ
Dai, CF
Kuo, YH
Sheu, JH
[J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (04): : 592 - 597
[2] 1α,3β,5β-Trihydroxy-24-methylenecholestan-6-one:: a novel steroid from a soft coral Sinularia gibberosa
Ahmed, AF
Dai, CF
Kuo, YH
Sheu, JH
[J]. STEROIDS, 2003, 68 (04) : 377 - 381
[3] ALLEY MC, 1988, CANCER RES, V48, P589
[4] Terpenoid constituents of Pellia epiphylla
Cullmann, F
Becker, H
[J]. PHYTOCHEMISTRY, 1998, 47 (02) : 237 - 245
[5] CLAVULARINS, A NEW CLASS OF CYTO-TOXIC COMPOUNDS ISOLATED FROM THE SOFT CORAL, CLAVULARIA-KOELLIKERI
ENDO, M
NAKAGAWA, M
HAMAMOTO, Y
NAKANISHI, T
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (06) : 322 - 323
[6] Five new antifouling sesquiterpenes from two marine sponges of the genus Axinyssa and the nudibranch Phyllidia pustulosa
Hirota, H
Okino, T
Yoshimura, E
Fusetani, N
[J]. TETRAHEDRON, 1998, 54 (46) : 13971 - 13980
[7] Hiroya K, 1999, SYNLETT, P529
[8] Hu LH, 1997, PHYTOCHEMISTRY, V44, P1287, DOI 10.1016/S0031-9422(96)00690-5
[9] GUAIANOLIDES AND OTHER CONSTITUENTS FROM LIABUM-FLORIBUNDUM
JAKUPOVIC, J
SCHUSTER, A
BOHLMANN, F
DILLON, MO
[J]. PHYTOCHEMISTRY, 1988, 27 (06) : 1771 - 1775
[10] KOBAYASHI M, 1989, CHEM PHARM BULL, V37, P1192

← 1 2 →