An efficient synthesis of neoflavonoid antioxidants based on Montmorillonite K-10 catalysis

被引:39
作者
Lee, JM [1 ]
Tseng, TH [1 ]
Lee, YJ [1 ]
机构
[1] Natl Changhua Univ Educ, Dept Chem, Changhua, Taiwan
来源
SYNTHESIS-STUTTGART | 2001年 / 15期
关键词
Montmorillonite K-10; 4-phenylneoflavonoids; Fries rearrangement;
D O I
10.1055/s-2001-18436
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new approach to synthesis of neoflavonoids, based on a high yielding Montmorillonite K-10 catalyzed lactone ring forming cyclization process, is described. The utility of this methodology is exemplified by its employment in the preparation of the substituted 4-phenylneoflavonoids 1-8. The free radical scavenging properties of these substances were evaluated. The neoflavonoids 1 and 5, which mimic esculetin-type antioxidants, were observed to quench hydrazyl free radicals.
引用
收藏
页码:2247 / 2254
页数:8
相关论文
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