An efficient synthesis of neoflavonoid antioxidants based on Montmorillonite K-10 catalysis

被引：39

作者：

Lee, JM ^{[1
]}

Tseng, TH ^{[1
]}

Lee, YJ ^{[1
]}

机构：

[1] Natl Changhua Univ Educ, Dept Chem, Changhua, Taiwan

来源：

SYNTHESIS-STUTTGART | 2001年 / 15期

关键词：

Montmorillonite K-10; 4-phenylneoflavonoids; Fries rearrangement;

D O I：

10.1055/s-2001-18436

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new approach to synthesis of neoflavonoids, based on a high yielding Montmorillonite K-10 catalyzed lactone ring forming cyclization process, is described. The utility of this methodology is exemplified by its employment in the preparation of the substituted 4-phenylneoflavonoids 1-8. The free radical scavenging properties of these substances were evaluated. The neoflavonoids 1 and 5, which mimic esculetin-type antioxidants, were observed to quench hydrazyl free radicals.

引用

页码：2247 / 2254

页数：8

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