MECHANISMS OF DISEASE Filaggrin Mutations Associated with Skin and Allergic Diseases

被引：839

作者：

Irvine, Alan D. ^{[1
,2
,3
]}

McLean, W. H. Irwin ^{[4
]}

Leung, Donald Y. M. ^{[5
,6
]}

机构：

[1] Our Ladys Hosp Sick Children, Natl Childrens Res Ctr, Dublin, Ireland

[2] Our Ladys Hosp Sick Children, Dept Paediat Dermatol, Dublin, Ireland

[3] Trinity Coll Dublin, Dept Clin Med, Dublin, Ireland

[4] Univ Dundee, Div Mol Med, Colleges Life Sci & Med Dent & Nursing, Dundee, Scotland

[5] Natl Jewish Hlth, Dept Pediat, Denver, CO 80206 USA

[6] Univ Colorado, Dept Pediat, Denver, CO 80202 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2011年 / 365卷 / 14期

基金：

英国医学研究理事会;

关键词：

OF-FUNCTION MUTATIONS; ATOPIC-DERMATITIS; STRATUM-CORNEUM; BARRIER FUNCTION; ICHTHYOSIS VULGARIS; CORNIFIED ENVELOPE; RISK-FACTOR; AUTOSOMAL-DOMINANT; FUNCTION VARIANTS; RARE MUTATIONS;

D O I：

10.1056/NEJMra1011040

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1315 / 1327

页数：13

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