Memory impairment in abstinent MDMA ("Ecstasy") users: A longitudinal investigation

被引:86
作者
Zakzanis, KK
Young, DA
机构
[1] Univ Toronto, Div Life Sci, Toronto, ON M1C 1A4, Canada
[2] Archway Clin, Ctr Addict & Mental Hlth, Toronto, ON, Canada
关键词
D O I
10.1212/WNL.56.7.966
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
To examine the neurotoxic potential of continued MDMA ("Ecstasy") use in humans and its functional consequences over the course of 1 year, 15 MDMA users participated in a longitudinal study in which they completed a brief neuropsychological test battery composed mainly of retrospective and prospective memory tasks. Subjects were abstinent for 2 weeks on initial and I-year testing. Continued use of MDMA was associated with progressive decline in terms of immediate and delayed recall.
引用
收藏
页码:966 / 969
页数:4
相关论文
共 9 条
[1]  
Aguirre N, 1997, J NEUROCHEM, V68, P1099
[2]   Memory impairment in abstinent MDMA ("Ecstasy") users [J].
Bolla, KI ;
McCann, UD ;
Ricaurte, GA .
NEUROLOGY, 1998, 51 (06) :1532-1537
[3]  
CHO KC, 1994, AMPHETAMINE ITS ANAL, P43
[4]  
FISCHER C, 1995, J NEUROSCI, V15, P5476
[5]   Memory deficits associated with recreational use of "ecstasy" (MDMA) [J].
Morgan, MJ .
PSYCHOPHARMACOLOGY, 1999, 141 (01) :30-36
[6]   Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits [J].
Parrott, AC ;
Lees, A ;
Garnham, NJ ;
Jones, M ;
Wesnes, K .
JOURNAL OF PSYCHOPHARMACOLOGY, 1998, 12 (01) :79-83
[7]   Memory disturbances in "Ecstasy" users are correlated with an altered brain serotonin neurotransmission [J].
Reneman, L ;
Booij, J ;
Schmand, B ;
van den Brink, W ;
Gunning, B .
PSYCHOPHARMACOLOGY, 2000, 148 (03) :322-324
[8]  
SCHMIDT CJ, 1987, J PHARMACOL EXP THER, V240, P1
[9]   CONTENTS OF ECSTASY [J].
WOLFF, K ;
HAY, AWM ;
SHERLOCK, K ;
CONNER, M .
LANCET, 1995, 346 (8982) :1100-1101