Meiosis: Cohesins Are Not Just for Sisters Any More

被引:6
作者
Cahoon, Cori K. [1 ]
Hawley, R. Scott [1 ,2 ]
机构
[1] Stowers Inst Med Res, Kansas City, MO 64110 USA
[2] Univ Kansas, Dept Mol & Integrat Physiol, Med Ctr, Kansas City, KS 66160 USA
关键词
SYNAPTONEMAL COMPLEX; DROSOPHILA OOCYTES; INITIATION; SYNAPSIS; ORD;
D O I
10.1016/j.cub.2016.05.011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Multiple meiosis-specific cohesion proteins act to facilitate homolog segregation at the first meiotic division. A recent paper demonstrates that meiotic cohesins can be separated into two complexes, one that establishes and maintains intersister cohesion and one that promotes interhomolog adhesion by regulating synaptonemal complex assembly.
引用
收藏
页码:R523 / R525
页数:3
相关论文
共 17 条
[1]   Identification of ORD, a Drosophila protein essential for sister chromatid cohesion [J].
Bickel, SE ;
Wyman, DW ;
Miyazaki, WY ;
Moore, DP ;
OrrWeaver, TL .
EMBO JOURNAL, 1996, 15 (06) :1451-1459
[2]   Regulating the construction and demolition of the synaptonemal complex [J].
Cahoon, Cori K. ;
Hawley, R. Scott .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2016, 23 (05) :369-377
[3]   Synaptonemal Complex Components Promote Centromere Pairing in Pre-meiotic Germ Cells [J].
Christophorou, Nicolas ;
Rubin, Thomas ;
Huynh, Jean-Rene .
PLOS GENETICS, 2013, 9 (12)
[4]   Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells [J].
Gause, Maria ;
Webber, Hayley A. ;
Misulovin, Ziva ;
Haller, Gabe ;
Rollins, Robert A. ;
Eissenberg, Joel C. ;
Bickel, Sharon E. ;
Dorsett, Dale .
CHROMOSOMA, 2008, 117 (01) :51-66
[5]   Dynamic and Stable Cohesins Regulate Synaptonemal Complex Assembly and Chromosome Segregation [J].
Gyuricza, Mercedes R. ;
Manheimer, Kathryn B. ;
Apte, Vandana ;
Krishnan, Badri ;
Joyce, Eric F. ;
Mckee, Bruce D. ;
McKim, Kim S. .
CURRENT BIOLOGY, 2016, 26 (13) :1688-1698
[6]   SMC1β-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction [J].
Hodges, CA ;
Revenkova, E ;
Jessberger, R ;
Hassold, TJ ;
Hunt, PA .
NATURE GENETICS, 2005, 37 (12) :1351-1355
[7]   Regulation of meiotic cohesion and chromosome core morphogenesis during pachytene in Drosophila oocytes [J].
Khetani, Radhika S. ;
Bickel, Sharon E. .
JOURNAL OF CELL SCIENCE, 2007, 120 (17) :3123-3137
[8]   Sisters Unbound Is Required for Meiotic Centromeric Cohesion in Drosophila melanogaster [J].
Krishnan, Badri ;
Thomas, Sharon E. ;
Yan, Rihui ;
Yamada, Hirotsugu ;
Zhulin, Igor B. ;
McKee, Bruce D. .
GENETICS, 2014, 198 (03) :947-+
[9]   The synaptonemal complex component C(2)M regulates meiotic crossing over in Drosophila [J].
Manheim, EA ;
McKim, KS .
CURRENT BIOLOGY, 2003, 13 (04) :276-285
[10]   Human aneuploidy: mechanisms and new insights into an age-old problem [J].
Nagaoka, So I. ;
Hassold, Terry J. ;
Hunt, Patricia A. .
NATURE REVIEWS GENETICS, 2012, 13 (07) :493-504