Breaking the WAVE complex:: the point of Arabidopsis trichomes

被引:117
作者
Szymanski, DB [1 ]
机构
[1] Purdue Univ, Dept Agron, W Lafayette, IN 47907 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.pbi.2004.11.004
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Actin filaments comprise an essential cytoskeletal array that organizes the cytoplasm during growth and cell division. In growing cells, actin filaments carry out many functions. Actin filaments position the endomembrane system and act as a substrate on which organelle motility occurs. Other actinfilament arrays appear to be more dynamic and to reorganize in response to growth signals and external cues. The diverse cellular functions of the actin cytoskeleton are mediated by actin-binding proteins that nucleate, destabilize, and bundle actin filaments. The distorted trichome morphology mutants provide a simple genetic system in which to study mechanisms of actin-dependent morphogenesis. Recent results from several groups indicate that 'distorted group' genes encode subunits of the actin-related protein (Arp)2/3 and WAVE complexes, and function in a cell morphogenesis pathway.
引用
收藏
页码:103 / 112
页数:10
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