Metabolomics: Current analytical platforms and methodologies

被引:800
作者
Dunn, WB [1 ]
Ellis, DI [1 ]
机构
[1] Univ Manchester, Sch Chem, Bioanalyt Sci Grp, Manchester M60 1QD, Lancs, England
基金
英国生物技术与生命科学研究理事会;
关键词
infrared spectroscopy; mass spectrometry; nuclear magnetic resonance spectroscopy; metabolic fingerprinting; metabolic profiling; metabolite; metabolome; metabolomics; metabonomics;
D O I
10.1016/j.trac.2004.11.021
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
During the previous decade, a new array of analytical methodologies and technologies were introduced related to the analysis of microbial, plant and animal metabolomes (complete collections of all low molecular weight compounds in a cell). The scientific field of metabolomics was born. In this review, we discuss advances in methodologies and technologies, and outline applications. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:285 / 294
页数:10
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