Applications of dendrimers in bio-organic chemistry

被引：130

作者：

Kim, Y ^{[1
]}

Zimmerman, SC ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1998年 / 2卷 / 06期

关键词：

D O I：

10.1016/S1367-5931(98)80111-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dendrimers represent a new class of highly branched polymers whose interior cavities and multiple peripheral groups facilitate potential applications in biomedicine and bio-organic chemistry. Major advances in the past year were made in the synthesis and study of new carbohydrate, nucleic acid, and peptide dendrimers, as well as in the use of dendrimers as magnetic resonance imaging contrast agents, as agents for cellular delivery of nucleic acids, and as scaffolds for biomimetic systems.

引用

收藏

页码：733 / 742

页数：10

相关论文

共 57 条

[21] Dendrimer-encapsulated iron porphyrin as a novel hemoprotein mimic for dioxygen binding [J].

Jiang, DL ;

Aida, T .

JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY, 1997, A34 (10) :2047-2055

[22] Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers [J].

KukowskaLatallo, JF ;

Bielinska, AU ;

Johnson, J ;

Spindler, R ;

Tomalia, DA ;

Baker, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) :4897-4902

[23] Gadolinium(III) DO3A macrocycles and polyethylene glycol coupled to dendrimers - Effect of molecular weight on physical and biological properties of macromolecular magnetic resonance imaging contrast agents [J].

Margerum, LD ;

Campion, BK ;

Koo, M ;

Shargill, N ;

Lai, JJ ;

Marumoto, A ;

Sontum, PC .

JOURNAL OF ALLOYS AND COMPOUNDS, 1997, 249 (1-2) :185-190

[24] Dendrophanes: Water-soluble dendritic receptors as models for buried recognition sites in globular proteins [J].

Mattei, S ;

Wallimann, P ;

Kenda, B ;

Amrein, W ;

Diederich, F .

HELVETICA CHIMICA ACTA, 1997, 80 (08) :2391-2417

[25] Dynamics of Bengal Rose encapsulated in the Meijer dendrimer box [J].

Miklis, P ;

Cagin, T ;

Goddard, WA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (32) :7458-7462

[26] Molecular diversity of novel amino acid based dendrimers [J].

Mulders, SJE ;

Brouwer, AJ ;

Liskamp, RMJ .

TETRAHEDRON LETTERS, 1997, 38 (17) :3085-3088

[27]

Newkome G.R., 1996, DENDRITIC MOL CONCEP

[28]

NEWKOME GR, 1992, SYNLETT, P53

[29]

Newkome GR, 1998, ANGEW CHEM INT EDIT, V37, P307, DOI 10.1002/(SICI)1521-3773(19980216)37:3<307::AID-ANIE307>3.0.CO

[30]

2-L

← 1 2 3 4 5 6 →