Bimetallic catalytic synthesis of annelated benzazepines

被引：21

作者：

Cleghorn, LAT

Grigg, R ^{[1
]}

Kilner, C

MacLachlan, WS

Sridharan, V

机构：

[1] Univ Leeds, Sch Chem, MIDAS Ctr, Leeds LS2 9JT, W Yorkshire, England

[2] GlaxoSmithKline, Harlow CM19 5AW, Essex, England

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 24期

关键词：

D O I：

10.1039/b503213j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel short synthetic route to annelated benzazepines, using additive enhanced palladium-indium catalytic 3-component cascade methodology is described.

引用

页码：3071 / 3073

页数：3

共 17 条

[1] Palladium-indium mediated Barbier-type allylation of aldehydes with allenes [J].

Anwar, U ;

Grigg, R ;

Rasparini, M ;

Savic, V ;

Sridharan, V .

CHEMICAL COMMUNICATIONS, 2000, (08) :645-646

[2] Palladium catalysed cyclisation-Barbier-type allylation cascades [J].

Anwar, U ;

Grigg, R ;

Sridharan, V .

CHEMICAL COMMUNICATIONS, 2000, (11) :933-934

[3] Umpolung of vinyloxiranes: Regio- and stereoselectivity of the In/Pd-mediated allylation of carbonyl compounds [J].

Araki, S ;

Kameda, K ;

Tanaka, J ;

Hirashita, T ;

Yamamura, H ;

Kawai, M .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (23) :7919-7921

[4] A new preparative method for allylic indium(III) reagents by reductive transmetalation of π-allylpalladium(II) with indium(I) salts [J].

Araki, S ;

Kamei, T ;

Hirashita, T ;

Yamamura, H ;

Kawai, M .

ORGANIC LETTERS, 2000, 2 (06) :847-849

[5] Three-component bimetallic (Pd/In) mediated cascade allylation of C=X functionality - Part 1. Scope and Class I examples with aldehydes and ketones [J].

Cleghorn, LAT ;

Cooper, IR ;

Fishwick, CWG ;

Grigg, R ;

MacLachlan, WS ;

Rasparini, M ;

Sridharan, V .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2003, 687 (02) :483-493

[6] Additive effects in palladium-indium mediated Barbier type allylations [J].

Cleghorn, LAT ;

Cooper, IR ;

Grigg, R ;

MacLachlan, WS ;

Sridharan, V .

TETRAHEDRON LETTERS, 2003, 44 (43) :7969-7973

[7] Diastereoselective Pd/In bimetallic inter-intramolecular (class 2) cascade reactions of allenyl-imines and aryl iodides [J].

Cooper, IR ;

Grigg, R ;

Hardie, MJ ;

MacLachlan, WS ;

Sridharan, V ;

Thomas, WA .

TETRAHEDRON LETTERS, 2003, 44 (11) :2283-2285

[8] 3-Component palladium-indium mediated diastereoselective cascade allylation of imines with allenes and aryl iodides [J].

Cooper, IR ;

Grigg, R ;

MacLachlan, WS ;

Thornton-Pett, M ;

Sridharan, V .

CHEMICAL COMMUNICATIONS, 2002, (13) :1372-1373

[9]

Cossy J, 1999, EUR J ORG CHEM, V1999, P1925

[10] A new cascade for the one-pot synthesis of linear homoallylic alcohols with an allylic diindium reagent [J].

Hirashita, T ;

Yamamura, H ;

Kawai, M ;

Araki, S .

CHEMICAL COMMUNICATIONS, 2001, (04) :387-388

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