Accelerated atherosclerosis in systemic lupus erythematosus: implications for patient management

被引:47
作者
Salmon, JE
Roman, MJ
机构
[1] Cornell Univ, Hosp Special Surg, Weill Med Coll, New York, NY 10021 USA
[2] Cornell Univ, New York Presbyterian Hosp, Weill Med Coll, Weill Cornell Med Ctr, New York, NY 10021 USA
关键词
D O I
10.1097/00002281-200109000-00001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
One of the most compelling clinical challenges in the management of systemic lupus erythematosus (SLE) is the high incidence of atherosclerotic cardiovascular disease (ASCVD). Potential mechanisms for accelerated atherosclerosis in SLE include chronic inflammation, excess of traditional risk factors, and corticosteroid therapy. Given the high prevalence of atherosclerosis in SLE patients relative to young women in the general population, we propose that the presence of SLE constitutes a sufficiently potent risk factor for ASCVD to warrant more aggressive goals for risk factor reduction and strategies to reduce inflammation.
引用
收藏
页码:341 / 344
页数:4
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