Import of proteins into mitochondria and chloroplasts

被引:41
作者
Haucke, V
Schatz, G
机构
[1] Biozentrum, University of Basel
关键词
D O I
10.1016/S0962-8924(96)10052-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Although mitochondria and chloroplasts synthesize some of their own proteins, they must import most of them from the cytosol. Import is mediated by molecular chaperones in the cytosol, receptors and channels in the organelle membranes and ATP-driven 'import motors' inside the organelles. Many of these components are now known, allowing informed guesses on how they might work.
引用
收藏
页码:103 / 106
页数:4
相关论文
共 39 条
[11]   MAS37P, A NOVEL RECEPTOR SUBUNIT FOR PROTEIN IMPORT INTO MITOCHONDRIA [J].
GRATZER, S ;
LITHGOW, T ;
BAUER, RE ;
LAMPING, E ;
PALTAUF, F ;
KOHLWEIN, SD ;
HAUCKE, V ;
JUNNE, T ;
SCHATZ, G ;
HORST, M .
JOURNAL OF CELL BIOLOGY, 1995, 129 (01) :25-34
[12]   RECONSTITUTION OF THE INITIAL STEPS OF MITOCHONDRIAL PROTEIN IMPORT [J].
HACHIYA, N ;
MIHARA, K ;
SUDA, K ;
HORST, M ;
SCHATZ, G ;
LITHGOW, T .
NATURE, 1995, 376 (6542) :705-709
[13]   The Mas20p and Mas70p subunits of the protein import receptor of yeast mitochondria interact via the tetratricopeptide repeat motif in Mas20p: Evidence for a single hetero-oligomeric receptor [J].
Haucke, V ;
Horst, M ;
Schatz, G ;
Lithgow, T .
EMBO JOURNAL, 1996, 15 (06) :1231-1237
[14]   THE YEAST MITOCHONDRIAL PROTEIN IMPORT RECEPTOR MAS20P BINDS PRECURSOR PROTEINS THROUGH ELECTROSTATIC INTERACTION WITH THE POSITIVELY CHARGED PRESEQUENCE [J].
HAUCKE, V ;
LITHGOW, T ;
ROSPERT, S ;
HAHNE, K ;
SCHATZ, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (10) :5565-5570
[15]   A receptor for protein import into potato mitochondria [J].
Heins, L ;
Schmitz, UK .
PLANT JOURNAL, 1996, 9 (06) :829-839
[16]   A RECEPTOR COMPONENT OF THE CHLOROPLAST PROTEIN TRANSLOCATION MACHINERY [J].
HIRSCH, S ;
MUCKEL, E ;
HEEMEYER, F ;
VONHEIJNE, G ;
SOLL, J .
SCIENCE, 1994, 266 (5193) :1989-1992
[17]   DYNAMIC INTERACTION OF THE PROTEIN TRANSLOCATION SYSTEMS IN THE INNER AND OUTER MEMBRANES OF YEAST MITOCHONDRIA [J].
HORST, M ;
HILFIKERROTHENFLUH, S ;
OPPLIGER, W ;
SCHATZ, G .
EMBO JOURNAL, 1995, 14 (10) :2293-2297
[18]   TRANSPORT AND ROUTING OF PROTEINS INTO CHLOROPLASTS [J].
KEEGSTRA, K .
CELL, 1989, 56 (02) :247-253
[19]   Cytoplasmic chaperones determine the targeting pathway of precursor proteins to mitochondria [J].
Komiya, T ;
Sakaguchi, M ;
Mihara, K .
EMBO JOURNAL, 1996, 15 (02) :399-407
[20]   Mechanisms of protein import across the mitochondrial outer membrane [J].
Lill, R ;
Neupert, W .
TRENDS IN CELL BIOLOGY, 1996, 6 (02) :56-61