Disequilibrium in distribution of resistance mutations among Mycobacterium tuberculosis Beijing and non-beijing strains isolated from patients in Germany

被引：57

作者：

Hillemann, D ^{[1
]}

Kubica, T ^{[1
]}

Rüsch-Gerdes, S ^{[1
]}

Niemann, S ^{[1
]}

机构：

[1] Forschungszentrum Borstel, Natl Ref Ctr Mycobacteria, D-23845 Borstel, Germany

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 03期

关键词：

D O I：

10.1128/AAC.49.3.1229-1231.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genotypic analysis of 103 multidrug-resistant Mycobacterium tuberculosis strains isolated in Germany in 2001 revealed that mutations in codon 531 (75.7%) of the rpoB gene and codon 315 (88.4%) of the katG gene are most frequent. Beijing genotype strains (60.2% of all isolates) displayed a different distribution of resistance mutations than non-Beijing strains.

引用

页码：1229 / 1231

页数：3

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