Evaluation of seaFAST, a rapid fluorescent in situ hybridization test, for detection of Helicobacter pylori and resistance to clarithromycin in paraffin-embedded biopsy sections

被引：30

作者：

Morris, JM

Reasonover, AL

Bruce, MG

Bruden, DL

McMahon, BJ

Sacco, FD

Berg, DE

Parkinson, AJ

机构：

[1] CDC, Arctic Invest Program, Anchorage, AK 99508 USA

[2] Alaska Native Tribal Hlth Consortium, Anchorage, AK USA

[3] Washington Univ, Sch Med, St Louis, MO 63130 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 07期

关键词：

D O I：

10.1128/JCM.43.7.3494-3496.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A commercially available rapid fluorescent in situ hybridization (FISH) test, (seaFAST H. pylori Combi-Kit; SeaPro Theranostics International, Lelystad, The Netherlands) was used to simultaneously detect the presence of Helicobacter pylori and determine clarithromycin susceptibility in paraffin-embedded biopsy sections. The FISH method was found to be 97% sensitive, 94% specific for the detection of H. pylori and comparable to agar dilution for the detection of resistance to clarithromycin.

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收藏

页码：3494 / 3496

页数：3

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