Daucane sesquiterpenes from Ferula hermonis

被引：45

作者：

Galal, AM ^{[1
]}

Abourashed, EA

Ross, SA

ElSohly, MA

Al-Said, MS

El-Feraly, FS

机构：

[1] Univ Mississippi, Dept Pharmacognosy, Natl Ctr Nat Prod Res, University, MS 38677 USA

[2] Univ Mississippi, Sch Pharm, Dept Pharmaceut, University, MS 38677 USA

[3] King Saud Univ, Coll Pharm, Dept Pharmacognosy, Riyadh 11451, Saudi Arabia

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 03期

关键词：

D O I：

10.1021/np000526x

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The roots of Ferula hermonis Boiss yielded two new daucane esters, 14-(4'-hydroxybenzoyloxy)dauc-4,8-diene (1) and 14-(4'-hydroxy-3'-methoxybenzoyloxy)dauc-4,8-diene (2), together with the four known sesquiterpenes jaeschkeanadiol p-hydroxybenzoate (3), jaeschkeanadiol benzoate (4), jaeschkeanadiol (5), and epoxyjaeschkeanadiol (6). The identities of the isolated compounds were ascertained primarily using NMR and MS data. Compounds 1 and 3 exhibited antimicrobial activity against Staphylococcus aureus with IC50 1.5 and 3.5 mug/mL, respectively, and against Methicillin-resistant S. aureus with IC50 2.0 and 4.0 mug/mL, respectively.

引用

页码：399 / 400

页数：2

共 14 条

[11] DAUCANE ESTERS FROM FERULA-COMMUNIS SUBSP COMMUNIS [J].

MISKI, M ;

MABRY, TJ .

PHYTOCHEMISTRY, 1985, 24 (08) :1735-1741

[12] NEW DAUCANE ESTERS FROM FERULA-TINGITANA [J].

MISKI, M ;

MABRY, TJ .

JOURNAL OF NATURAL PRODUCTS, 1986, 49 (04) :657-660

[13] FERCOLIDE, A TYPE OF SESQUITERPENE LACTONE FROM FERULA-COMMUNIS SUBSP COMMUNIS AND THE CORRECT STRUCTURE OF VAGINATIN [J].

MISKI, M ;

MABRY, TJ .

PHYTOCHEMISTRY, 1986, 25 (07) :1673-1675

[14] A NEW SESQUITERPENE ESTER FROM FERULA-TINGITANA [J].

MISKI, M ;

ULUBELEN, A ;

MABRY, TJ ;

WATSON, WH ;

VICKOVIC, I ;

HOLUB, M .

TETRAHEDRON, 1984, 40 (24) :5197-5201

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