Microchannel plate detectors for 14C autoradiography

被引：24

作者：

Lees, JE

Fraser, GW

Carthew, P

机构：

[1] Univ Leicester, Dept Phys & Astron, Xray Astron Grp, Leicester LE1 7RH, Leics, England

[2] MRC, Toxicol Unit, Leicester LE1 9HN, Leics, England

来源：

IEEE TRANSACTIONS ON NUCLEAR SCIENCE | 1998年 / 45卷 / 03期

关键词：

D O I：

10.1109/23.682018

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We describe a new type of detector for digital autoradiography which combines high sensitivity, useful detecting area (93 x 93mm) and good spatial resolution (< 100 mu m). This instrument is suitable, inter alia, for imaging beta-emitting whole body thin tissue slices. Measured detector sensitivity and linearity derived from images of a C-14 standard are presented. We also describe results from (i) a C-14 labelled rat whole body slice showing selective radiopharmaceutical uptake in clearly identifiable organs and (ii) C-14-Tamoxifen doped semi-thin tissue sections of rat womb and liver.

引用

收藏

页码：1288 / 1292

页数：5

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