Tumoral and Normal Cells Treatment With High-Voltage Pulsed Cold Atmospheric Plasma Jets

被引：95

作者：

Georgescu, Nicolae ^{[1
]}

Lupu, Andreea Roxana ^{[1
]}

机构：

[1] Natl Inst Laser Plasma & Radiat Phys, Bucharest 76900, Romania

来源：

IEEE TRANSACTIONS ON PLASMA SCIENCE | 2010年 / 38卷 / 08期

关键词：

Cells apoptosis; cold atmospheric plasma jets; pulsed high voltage; NEEDLE;

D O I：

10.1109/TPS.2010.2041075

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

High-voltage pulsed cold atmospheric plasma jets were used to treat tumoral (B16 and COLO320) and normal (macrophage) cells. Cold atmospheric plasma jet generator and plasma jet physical characteristics are presented. The treatment of the tumoral cells intended to obtain their apoptosis. For tumoral cells, percents of up to 70% apoptosis have been obtained, using helium plasma, activated with up to 2% oxygen. In the same experimental conditions, the plasma treatment did not induce apoptosis in normal (macrophage) cells. In addition, the macrophage cells were not activated by the plasma jets.

引用

页码：1949 / 1955

页数：7

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