Cannabis and alcohol - a close friendship

被引：45

作者：

Mechoulam, R ^{[1
]}

Parker, L

机构：

[1] Hebrew Univ Jerusalem, Fac Med, Sch Pharm, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel

[2] Wilfrid Laurier Univ, Dept Psychol, Waterloo, ON N2L 3C5, Canada

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2003年 / 24卷 / 06期

关键词：

D O I：

10.1016/S0165-6147(03)00107-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cannabinoids and alcohol activate the same reward pathways, and the cannabinoid CB1 receptor system plays an important role in regulating the positive reinforcing properties of alcohol. Indeed, both cannabinoids and alcohol cause the release of dopamine in the nucleus accumbens. Recent research suggests that ethanol preference, which is dependent on CB, receptors, is higher in young mice than in old mice, and higher in female mice than in male mice.

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收藏

页码：266 / 268

页数：3

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