Antioxidant activity of Cassia fistula (Linn.) flowers in alloxan induced diabetic rats

被引：66

作者：

Manonmani, G

Bhavapriya, V

Kalpana, S

Govindasamy, S

Apparanantham, T

Aqueous

机构：

[1] Univ Madras, Dept Biochem & Mol Biol, Madras 600025, Tamil Nadu, India

[2] Cent Res Inst Siddha, Madras 600106, Tamil Nadu, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2005年 / 97卷 / 01期

关键词：

Cassia fistula; alloxan; diabetes; lipid peroxidation; antioxidant enzymes;

D O I：

10.1016/j.jep.2004.09.051

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Aqueous extract of Cassia fistula (Linn.) flowers (ACF) was screened for its antioxidant effect in alloxan induced diabetic rats. An appreciable decrease in peroxidation products viz thiobarbituric acid reactive substances, conjugated dienes, hydroperoxides was observed in heart tissues of ACF treated diabetic rats. The decreased activities of key antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione, reductase and glutathione in diabetic rats were brought back to near normal range upon ACF treatment. These results suggest that ACF has got promising antioxidative activity in alloxan diabetic rats. (C) 2004 Published by Elsevier Ireland Ltd.

引用

页码：39 / 42

页数：4

共 38 条

[1] Evaluation of the efficacy of Lawsonia alba in the alleviation of carbon tetrachloride-induced oxidative stress [J].